High dose cisplatin head and neck

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August undefined, 2024

Web8 de nov. de 2024 · Cisplatin-based chemoradiotherapy is a well established standard of care in non-operated patients, but carrying substantial toxicity when compared to radiotherapy alone. However, a large proportion of patients are not suitable for receiving high-dose cisplatin-based chemotherapy either due to age, general and/or medical …

Treatment outcomes of standard (high dose) cisplatin and …

http://www.nrgoncology.org/Home/News/Post/comparing-high--and-low-dose-cisplatin-for-patients-with-locoregionally-advanced-squamous-cell-carcinoma-of-the-head-and-neck-nrg-hn009 Web12 de jan. de 2009 · To compare the progression-free survival (PFS) of patients with locally advanced squamous cell carcinoma of the head and neck treated with standard fractionation radiotherapy and high-dose cisplatin vs accelerated fractionation radiotherapy and panitumumab. Secondary. To compare overall survival of patients treated with these … iphone sous blister

Comparing High- and Low-Dose Cisplatin for Patients with ... - NRG

WebThe treatment of locally advanced head and neck cancer (HNC) is based on extensive resections followed by concurrent chemoradiotherapy (CRT) with platinum derivatives or … Web7 de jan. de 2024 · McKibbin et al 6 also found a nephroprotective effect of mannitol in their study of SCCHN patients receiving high dose of cisplatin. The aim of this study was to compare changes in 51 Cr-EDTA clearance and estimated glomerular filtration rate (eGFR) in head and neck cancer patients receiving either saline hydration with mannitol or … WebObjectives: Cisplatin-induced ototoxicity is a common permanent consequence of curative chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). Predictors of ototoxicity in HNSCC were examined. Materials and methods: In this prospective, observational cohort study, 206 adult HNSCC patients underwent … orange juice packet

Rapid superselective high‐dose cisplatin infusion for advanced …

WebWe examined 79 patients with inoperable stage IV head and neck cancer receiving intra-arterial infusion of high-dose cisplatin (150 mg/m 2) on days 2, 9, 16, and 23 … Web16 de fev. de 2016 · Methods: 208 patients with advanced-stage malignancies of the head and neck region were evaluated. All patients were treated with high-dose cisplatin CCRT. The main outcome parameters were nephrotoxicity (defined as creatinine clearance grade 2 or more) and cumulative doses of cisplatin and radiation. orange juice out after washingWeb28 de mar. de 2024 · Background. No randomized studies have compared low‐dose or high‐dose concurrent chemoradiotherapy (CRT). Methods. In this study, 7219 patients … iphone sound wave form

"Web3 de set. de 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a … " - High dose cisplatin head and neck

High dose cisplatin head and neck

Frontiers Cisplatin Eligibility Issues and Alternative Regimens in ...

Web11 de fev. de 2024 · Concurrent chemoradiotherapy with cisplatin is standard for patients (pts) with loco-regionally advanced squamous cell carcinoma of the head and neck (LA … WebObjectives: Cisplatin-induced ototoxicity is a common permanent consequence of curative chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). …

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Web10 de abr. de 2024 · High-Dose Cisplatin for Head and Neck Cancer Lives On. High-Dose Cisplatin for Head and Neck Cancer Lives On J Clin Oncol. 2024 Apr 10;36(11):1055 … WebBackground: No randomized studies have compared low-dose or high-dose concurrent chemoradiotherapy (CRT). Methods: In this study, 7219 patients with stage III or IV head …

Web16 de fev. de 2016 · Methods: 208 patients with advanced-stage malignancies of the head and neck region were evaluated. All patients were treated with high-dose cisplatin … WebIn 22 patients with advanced squamous cell carcinoma of the head and neck we evaluated the efficacy and toxicity of 200 mg/m2 cisplatin administered in 3% NaCl with vigorous hydration. Six patients had previously untreated stage IV disease and 16 patients had recurrent disease, including eight with prior chemotherapy including low-dose cisplatin …

WebBackground: Three-weekly high-dose cisplatin (100 mg/m 2) is considered the standard systemic regimen given concurrently with postoperative or definitive radiotherapy in … WebThe association of pretreatment low skeletal muscle mass with chemotherapy dose-limiting toxicity in patients with head and neck cancer undergoing primary chemoradiotherapy …

Web29 de set. de 2015 · Introduction. High-dose cisplatin (CDDP)-based chemoradiotherapy (CRT) has significantly improved overall survival (OS), progression-free survival (PFS) and locoregional control compared with that observed with radiotherapy (RT) alone in patients with locally advanced squamous cell carcinoma of the head and neck (LASCCHN) …

WebHead and neck squamous cell carcinoma locally advanced definitive ciSplatin (three weekly) chemoradiation. ID: 291 v.6. Endorsed. Essential Medicine List. Head and neck cancer treatment is complex and combined modality therapy is common; the involvement of a multidisciplinary team (MDT) in the initial development and ongoing evaluation of the ... iphone sound turned offWeb3 de mai. de 2024 · Forastiere AA, Leong T, Rowinsky E, et al. Phase III comparison of high-dose paclitaxel + cisplatin + granulocyte colony-stimulating factor versus low-dose paclitaxel + cisplatin in advanced head and neck cancer: Eastern Cooperative Oncology Group Study E1393. J Clin Oncol. 2001 Feb 15. 19(4):1088-95. [QxMD MEDLINE Link]. orange juice packsWeb12 de abr. de 2024 · Head Neck 42(9), 2614–2625 (2024).Crossref, Medline, Google Scholar; 32. Bril SI, Al-Mamgani A, Chargi N et al. The association of pretreatment low skeletal muscle mass with chemotherapy dose-limiting toxicity in patients with head and neck cancer undergoing primary chemoradiotherapy with high-dose cisplatin. Head … orange juice on whole30Web13 de abr. de 2024 · Head and neck squamous cell carcinoma (HNSCC) is among the most severe and complex malignant diseases with a high level of heterogeneity and, as a … iphone sounds muffled on callsWeb8 de nov. de 2024 · Three-weekly high-dose cisplatin (100 mg/m2) is considered the standard systemic regimen given concurrently with postoperative or definitive radiotherapy in locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN). Concurrent chemoradiation (CRT) with high-dose cisplatin is associated with significant acute and … orange juice peach schnappsWeb10 de abr. de 2024 · Weekly low-dose versus three-weekly high-dose cisplatin for concurrent chemoradiation in locoregionally advanced non-nasopharyngeal head and neck cancer: a systematic review and meta-analysis of aggregate data. Oncol. 2024; 22: ... HNC = Head and neck cancer, ... iphone source filterWebIn 22 patients with advanced squamous cell carcinoma of the head and neck we evaluated the efficacy and toxicity of 200 mg/m2 cisplatin administered in 3% NaCl with vigorous … orange juice ph number